15 Feb 2020, Φ Probabilistic Methods in Toxicology

15 Feb 2020, Φ Probabilistic Methods in Toxicology (updated version published)

Based on predecessors (2004 in German, 2014 in English), an updated version of the book chapter was published online today:

  • Mekel O, Fehr R (2020): Probabilistic Methods in Toxicology. Chapter in: Reichl F.-X. , Schwenk M. (eds.), Regulatory Toxicology. Rev. edition. Springer-Verlag GmbH Germany, part of Springer Nature, https://doi.org/10.1007/978-3-642-36206-4_47-2. For the chapter: first online 15 Feb 2020. [12-03]

This is a revised version of: Mekel, O., Fehr, R. (2014): Probabilistic methods in toxicology. Chapter in: Reichl, F.X., Schwenk, M. (eds.): Regulatory toxicology. Springer-Verlag, Berlin, Heidelberg, pp.253-259. Originally: Mekel, O., Fehr, R. (2004): Probabilistische Methoden. Kapitel 2.3.4 In: Reichl, F.-X., Schwenk, M. (Hrsg.): Regulatorische Toxikologie – Umweltschutz, Gesundheitsschutz, Verbraucherschutz. Springer, Berlin, pp.202-209.

Chapter structure:

  • Background
  • Methods for Quantifying Variability and Uncertainty in Risk Assessmen
    • Point Estimates
    • Probabilistic Estimates
    • Sensitivity Analysis
  • Application Potential in Dose–Response Assessment
  • Software for Probabilistic Exposure and Risk Assessment
  • Cross-Reference
  • References